Indiegogo is committed to accessibility. If you have difficulty using our site, please contact support@indiegogo.com for assistance or view our accessibility notice by clicking here

This campaign is closed

Tisch MSRCNY FDA-Approved Stem Cell Trial for MS

Help us make stem cell history! Support this Phase I adult stem cell clinical trial to treat MS...

You may also be interested in

Closed
Closed
Closed
Closed
Closed

Tisch MSRCNY FDA-Approved Stem Cell Trial for MS

Tisch MSRCNY FDA-Approved Stem Cell Trial for MS

Tisch MSRCNY FDA-Approved Stem Cell Trial for MS

Tisch MSRCNY FDA-Approved Stem Cell Trial for MS

Tisch MSRCNY FDA-Approved Stem Cell Trial for MS

Help us make stem cell history! Support this Phase I adult stem cell clinical trial to treat MS...

Help us make stem cell history! Support this Phase I adult stem cell clinical trial to treat MS...

Help us make stem cell history! Support this Phase I adult stem cell clinical trial to treat MS...

Help us make stem cell history! Support this Phase I adult stem cell clinical trial to treat MS...

Dr. Saud A. Sadiq
Dr. Saud A. Sadiq
Dr. Saud A. Sadiq
Dr. Saud A. Sadiq
1 Campaign |
New York, United States
$317,540 USD 960 backers
105% of $300,000 Flexible Goal Flexible Goal

Because of the generosity of our wonderful community of devoted friends, WE REACHED OUR GOAL of $300,000. The Tisch MS Research Center is grateful for the tremendous support the trial has received. However, funding is still critically needed for the study and our stem cell research program, so please continue to donate and make an impact on our progress in treating MS. Thank you from the bottom of our hearts for making a difference in MS research and joining our mission to eradicate MS.

To make a gift, please go to the Tisch MS Research Center Donation Page.

REPAIR, REGENERATE & RENEW: Cutting-Edge Stem Cell Research at
Tisch MS Research Center of New York

In 2013, Tisch MSRCNY made stem cell science history.

Our adult stem cell treatment received FDA approval for a Phase I Clinical Trial that has the potential to repair the damage caused by MS.

This exciting milestone took over ten years to reach and brings indescribable hope to MS patients and their loved ones all over the world.

REPAIR

Our stem cell therapy is the star of the research program at the Tisch MS Research Center of New York (Tisch MSRCNY), a 501(c)(3), independent, non-profit research center dedicated to finding the cause of and cure for multiple sclerosis (MS). The Center focuses on patient-based research, bringing findings rapidly from the laboratory into clinical application to treat symptoms of MS and to halt or reverse damage caused by the disease.

About MS
MS is an autoimmune disease of the central nervous system (CNS) that attacks the myelin sheath that surrounds axons around nerves and can cause numbness, pain, vision loss, difficulty walking, and even paralysis.
  •  MS affects 2.3 million people worldwide
  •  Over 400,000 people in the U.S. suffer from MS
  •  Every week, approximately 200 people are diagnosed with MS
  •  MS affects young adults in their prime as most are diagnosed between age  20-40
  •  MS affects twice as many women than men
  •  The cause of MS is not yet known
  •  Although there are some treatments that may halt progression, there is no cure for MS
In 2003, Drs. Saud A. Sadiq, Violaine Harris and their research team began leading the stem cell science revolution by conducting research on strategies to repair the damage caused by MS.

REGENERATE

In 2007, we started the process of obtaining FDA approval for a Phase I clinical trial. Finally, in August 2013, we received FDA approval to move ahead!
  • The objective of the Phase I trial is to test safety.
  • Data from the Phase I trial will lead to an improved strategy for Phase II
  • Positive outcomes of the trial may indicate the use of this therapy in other neurological diseases like ALS and Parkinson's Disease, cerebral palsy and spinal cord injuries.

Why Stem Cells?
In pre-clincal, non-human experiments of our stem cell therapy, renewal, repair and regeneration of myelin occurred in the CNS after intrathecal (via spinal fluid, not intravenous) injection.

From our preclinical models, we know that stem cells injected into the spinal fluid can have significant benefit in terms of improved neurological symptoms.

MS is characterized by brain inflammation, loss of myelin, damage to oligodendrocytes (the cells that make myelin), damage to neurons, and scar formation in the brain. As a result, nerve signals are not properly conducted, causing loss of neurological function. Stem cells are hypothesized to promote repair in MS by migrating to areas of demyelination, blocking damage-forming events, and enabling repair.
Why Neural Stem Cells?
Our unique clinical trial uses adult autologous bone marrow-derived mesenchymal stem cells as a source for neural progenitors (MSC-NPs) to promote myelin repair that can potentially reverse or prevent disability in MS patients. Tisch MSRCNY is the only MS Center that has received FDA approval for a stem cell therapy using MSC-NPs for MS patients

Procedure

  • Bone marrow is taken from patient's hip or sternum
  • The sample is taken to the laboratory to isolate and expand the mesenthymal stem cells (MSCs)
  • Neural progenitors (NPs) are derived from the MSCs to produce MSC-NPs
  • MSC-NPs are injected into the patient's spinal fluid
  • This process is repeated once every three months

RENEW 

We are eager to start the study.

There's only one thing we now critically need: FUNDING

We are applying for grants from federal, state and private entities to help fund the multi-phase study. To get started, we need to equip our lab with essential supplies listed below to conduct the study on the 20 patients.



The cost for each treatment is approximately $10,000, so the total cost for 20 patients who receive 3 treatments each for Phase I is approximately $600,000.

REASONS TO GIVE

  • Tisch MSRCNY has not received federal, state, or corporate funding to cover costs of this study, including supplies, insurance and labor costs
  • It is critical to move this clinical trial through the necessary phases of testing in order to validate it as a standard treatment
  • Drive progress in MS research
  • Advance the field of regenerative neurology
  • Increase knowledge of stem cell science
  • Make a direct impact on advancements in MS
  • Bring hope to those who suffer from MS and make a difference in their lives

REACT 

Be a part of the stem cell revolution!

  • Share this campaign with Friends on Facebook and Twitter
  • Recommend us on Google+
  • Embed this page on your website or blog
  • Email your friends and family to support innovative stem cell research

Please note: donating to this campaign will not influence patient recruitment or enrollment in the study.

Read on about our remarkable Center and the stem cell study on the other pages of this campaign!



RESEARCH TEAM

Looking for more information? Check the project FAQ
Need more information
Let us know if you think this campaign contains prohibited content.

Choose your Perk

featured

Stem Cell Star

$100 USD
Thank you for your support! You are playing a vital role in the stem cell science revolution. You will receive a personal thank you note from Tisch MSRCNY along with a beautiful 4-color, 5"x7" photograph of a stem cell. In addition, you will be mentioned on the Tisch MSRCNY Indiegogo campaign page and receive a weekly email update about the campaign that includes your name in the thank you section.
Estimated Shipping
May 2014
198 claimed

Stem Cell Supporter

$25 USD
Thank you for your support! Your name will be listed on the Tisch MSRCNY Indiegogo campaign page. You will also receive a weekly email update about the campaign including your name in the "thank you" section.
171 claimed

Donor of the Week

$250 USD
Thank you for your support! Your generosity will be acknowledged in a tweet out to our community. You will also be mentioned on the Tisch MSRCNY Indiegogo Campaign page and receive a weekly email update about the campaign that includes your name in the thank you section. You will also receive a personal thank you note along with a beautiful 4-color, 5"x7" photograph of a stem cell.
50 claimed

Symposium Partner

$500 USD
Thank you for your support! Your name will be printed in our patient Symposium program. The event takes place on Oct. 19 in New York City and is attended by over 1,000 members of our community from all over the world. You will also be mentioned on the Campaign page and receive a weekly email update about the campaign that includes your name in the thank you section. You will also receive the Tisch MSRCNY quarterly newsletter and be listed in the donor section of the Summer issue.
29 claimed

Honor Donor

$1,000 USD
Thank you for your support! You can give a gift in honor or in memory of a loved one. This special person will be notified of your kindness with a personal card from Tisch MSRCNY. You will also receive the Tisch MSRCNY quarterly newsletter and be listed in the donor section of the Summer 2014 issue.
16 claimed

Tour Tisch MSRCNY

$2,500 USD
Thank you for your support! You are invited to take a tour of Tisch MSRCNY, a state-of-the-art research facility that conducts innovative research on MS to find the cause of and cure for the disease and discover effective treatments for patients. After the tour, you will be invited to attend a dessert reception and Q&A with the Tisch MSRCNY research team. You will also receive the Tisch MSRCNY quarterly newsletter and be listed in the donor section of the Summer 2014 issue.
4 claimed

Article Dedication

$5,000 USD
Thank you for your support! You will be part of scientific research history as your name will appear in the dedication section of our next research publication to acknowledge the important role you are playing to advance MS research.You are also invited on a private tour of Tisch MSRCNY and a dessert reception and Q&A with the Tisch MSRCNY research team.
2 claimed

Evening With the Researchers

$10,000 USD
Thank you for your support! You can attend an invitation-only event with the researchers, including a cocktail reception, lab tour and presentations by the leading Principal Investigators for Tisch MSRCNY. You will also receive the Tisch MSRCNY quarterly newsletter and be listed in the donor section of the Summer 2014 issue.
1 claimed

Private tour with Dr. Sadiq

$25,000 USD
Thank you for your support! Dr. Saud A. Sadiq, a world renowned research scientist and physician who has devoted most of his medical career to treating patients with MS and finding the cause of and cure for the disease, will give you a tour of the lab along with Dr. Violaine Harris, Senior Research Scientist. Lunch will be provided.
1 claimed
Tags for this project

You may also be interested in

Up Caret